Chronic Obstructive Pulmonary Disease (COPD) – GSK 222714-222725
The aim of this study is to assess the efficacy and safety of Depemokimab compared as an add-on medicine in participants with uncontrolled moderate to severe COPD with type 2 inflammation.
Inclusion Criteria:
- Participants must be greater than or equal to (>=) 40 to less than or equal to (<=) 80 years of age, at the time of signing the Informed consent
- Elevated Blood Eosinophil Count (BEC)
- Moderate to severe COPD with frequent exacerbations
- COPD assessment test (CAT) score >=10 at Visit 1
- Smoking status: Current or former cigarette smokers with a history of cigarette smoking of >=10 pack-years.
- Participants should be on optimized inhaler therapy
- Body mass index (BMI) >=16 kilogram per square meter (kg/m^2)
- Male and eligible female participants
- Other criteria may apply
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