Systemic Lupus Erythematosus- Cartesian DC08-SLE-001
Participating in a clinical trial with Profound means making a real difference in the lives of others facing similar health challenges.
This is a Phase II study to evaluate the safety, tolerability and manufacturing feasibility of Descartes-08 CAR T-cells in patients with Systematic Lupus erythematosus (SLE).
Inclusion Criteria:
- Patient must be at least 18 years of age.
- Patient must have systemic lupus erythematosus (SLE) at the time of screening.
- Active symptoms despite recent or ongoing immunosuppressive therapy with glucocorticoids and at least 2 other immunosuppressive medications being tried for at least 12 weeks within 24 months of screening.
- At least one of: anti-dsDNA, anti-histone, anti-chromatin, and/or anti-Sm antibodies detectable at screening as assessed by a CLIA-certified laboratory.
Complete the form to get connected with new research studies and our team will reach out soon to help determine your eligibility.