Systemic Lupus Erythematosus- Cartesian DC08-SLE-001

Participating in a clinical trial with Profound means making a real difference in the lives of others facing similar health challenges.

This is a Phase II study to evaluate the safety, tolerability and manufacturing feasibility of Descartes-08 CAR T-cells in patients with Systematic Lupus erythematosus (SLE).

Inclusion Criteria:

  • Patient must be at least 18 years of age.
  • Patient must have systemic lupus erythematosus (SLE) at the time of screening.
  • Active symptoms despite recent or ongoing immunosuppressive therapy with glucocorticoids and at least 2 other immunosuppressive medications being tried for at least 12 weeks within 24 months of screening.
  • At least one of: anti-dsDNA, anti-histone, anti-chromatin, and/or anti-Sm antibodies detectable at screening as assessed by a CLIA-certified laboratory.

Call us at 619-489-5613 or complete the form and our team will reach out soon to help determine your eligibility.

Trial Interest Form